Tumor Suppressors and Endodermal Differentiation of P19 Embryonic Stem Cells
نویسندگان
چکیده
منابع مشابه
Tumor Suppressors and Endodermal Differentiation of P19 Embryonic Stem Cells
The P19 embryonic stem (ES) cells are derivatives of the inner cell mass of a mouse blastoderm, are multipotent and can give rise to all three germ layers [1]. They are anchorage-independent, display no contact inhibition, and are tumorigenic [2]. The P19 ES cell line was originally derived from a teratocarcinoma in C3H/HE mice, produced by grafting an embryo at 7 days of gestation to the teste...
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We recently discovered the existence of the oxytocin/oxytocin receptor (OT/OTR) system in the heart. Activation of cardiac OTR stimulates the release of atrial natriuretic peptide (ANP), which is involved in regulation of blood pressure and cell growth. Having observed elevated OT levels in the fetal and newborn heart at a stage of intense cardiomyocyte hyperplasia, we hypothesized a role for O...
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ژورنال
عنوان ژورنال: Cell & Developmental Biology
سال: 2015
ISSN: 2168-9296
DOI: 10.4172/2168-9296.1000e138